Suppose you have craeated, rigged and animated character in blender.
Render character animation from all 8 sides (up, down, left, right, upper left, upper right, down right, down left).
(you can use script automation for that)
Create sprite sheet for each side (so you will have 8 sprite sheets). You can use program to automate that.
Create JSON file, where for each side will be defined the size of one frame, and frame count, also an animation speed.
You can have a look in resources on game server, where these JSONs are to see the structure
Upload sheets + JSON on server
In TextureDatabase, add line to load the particular texture
In AnimationPackDatabase, add line to load the particular JSON and define actions